Saturday, August 11, 2012

Future Foods




 The truth is that we are still a long way from having to make much in the way of radical changes, but it is sometimes fun to pretend. Just recall that every hectare of tropical soil can support a family using the biochar protocol and even depending on present cropping and animal husbandry regimes. What we have successfully worked to the present are those soils that are particularly forgiving.

In the meantime increasing attention is been applied to insects. This has huge promise not least because of their ability to convert biomass into high quality protein, but the sheer weight of their presence on Earth. They are quite capable of supplying all the high quality protein for a human population of 100 billion which would otherwise be challenging.

Seaweed is barely tapped also as is noted here.

The moment we step outside our traditional paradigms, it becomes surprisingly easy to produce food stocks. Our own efforts have identified a multiproduct agriculture for the boreal forest. I began with low expectations and a generally unpromising environment. Yet it will be no more difficult than any other agricultural development. You just will not be growing mangos.

Future foods: What will we be eating in 20 years' time?

By Denise WintermanBBC News Magazine

29 July 2012 Last updated at 19:09 ET


Volatile food prices and a growing population mean we have to rethink what we eat, say food futurologists. So what might we be serving up in 20 years' time?

It's not immediately obvious what links Nasa, the price of meat and brass bands, but all three are playing a part in shaping what we will eat in the future and how we will eat it.

Rising food prices, the growing population and environmental concerns are just a few issues that have organisations - including the United Nations and the government - worrying about how we will feed ourselves in the future.

In the UK, meat prices are anticipated to have a huge impact on our diets. Some in the food industry estimate they could double in the next five to seven years, making meat a luxury item.

"In the West many of us have grown up with cheap, abundant meat," says food futurologist Morgaine Gaye.

"Rising prices mean we are now starting to see the return of meat as a luxury. As a result we are looking for new ways to fill the meat gap."

So what will fill such gaps and our stomachs - and how will we eat it?

Insects

Insects, or mini-livestock as they could become known, will become a staple of our diet, says Gaye.

It's a win-win situation. Insects provide as much nutritional value as ordinary meat and are a great source of protein, according to researchers at Wageningen University in the Netherlands. They also cost less to raise than cattle, consume less water and do not have much of a carbon footprint. Plus, there are an estimated 1,400 species that are edible to man.

Gaye is not talking about bushtucker-style witchetty grubs arriving on a plate near you. Insect burgers and sausages are likely to resemble their meat counterparts.

"Things like crickets and grasshoppers will be ground down and used as an ingredient in things like burgers."

The Dutch government is putting serious money into getting insects into mainstream diets. It recently invested one million euros (£783,000) into research and to prepare legislation governing insect farms.

A large chunk of the world's population already eat insects as a regular part of their diet. Caterpillars and locusts are popular in Africa,wasps are a delicacy in Japan, crickets are eaten in Thailand.

But insects will need an image overhaul if they are to become more palatable to the squeamish Europeans and North Americans, says Gaye, who is a member of the Experimental Food Society.
"They will become popular when we get away from the word insects and use something like mini-livestock."

Sonic-enhanced food

It's well documented how the appearance of food and its smell influence what we eat, but the effect sound has on taste is an expanding area of research. A recent study by scientists at Oxford University found certain tones could make things taste sweeter or more bitter.

"No experience is a single sense experience," says Russell Jones, from sonic branding company Condiment Junkie, who were involved in the study. "So much attention is paid to what food looks like and what it smells like, but sound is just as important."

The Bittersweet Study, conducted by Charles Spence, a professor of experimental psychology at Oxford University, found the taste of food could be adjusted by changing the sonic properties of a background soundtrack.

"We're not entirely sure what happens in brain as yet, but something does happen and that's really exciting," says Jones.

Sound and food have been experimented with by chef Heston Blumenthal. His Fat Duck restaurant has a dish called the Sound of the Sea, which is served with an iPod playing sounds of the seaside. The sounds reportedly make the food taste fresher.

But more widespread uses are developing. One that could have an important impact is the use of music to remove unhealthy ingredients without people noticing the difference in taste.

"We know what frequency makes things taste sweeter," says Jones, also a member of the Experimental Food Society. "Potentially you could reduce the sugar in a food but use music to make it seem just as sweet to the person eating it."

Companies are also increasingly using the link between food and sound in packaging. One crisp company changed the material it used to make packets as the cruncher sound made the crisps taste fresher to consumers. Recommended playlists could also appear on packaging to help enhance the taste of the product.

Jones says the use of sound is even being applied to white goods. Companies are looking into the hum fridges make, as a certain tone could make people think their food is fresher.

Lab-grown meat

Earlier this year, Dutch scientists successfully produced in-vitro meat, also known as cultured meat. They grew strips of muscle tissue using stem cells taken from cows, which were said to resemble calamari in appearance. They hope to create the world's first "test-tube burger" by the end of the year.

The first scientific paper on lab-grown meat was funded by Nasa, says social scientist Dr Neil Stephens, based at Cardiff University's ESRC Cesagen research centre. It investigated in-vitro meat to see if it was a food astronauts could eat in space.

Ten years on and scientists in the field are now promoting it as a more efficient and environmentally friendly way of putting meat on our plates.

A recent study by Oxford University found growing meat in a lab rather than slaughtering animals would significantly reduce greenhouse gases, along with energy and water use. Production also requires a fraction of the land needed to raise cattle. In addition it could be customised to cut the fat content and add nutrients.

Prof Mark Post, who led the Dutch team of scientists at Maastricht University, says he wants to make lab meat "indistinguishable" from the real stuff, but it could potentially look very different. Stephens, who is studying the debate over in-vitro meat, says there are on-going discussions in the field about what it should look like.

He says the idea of such a product is hard for people to take on board because nothing like it currently exists.

"We simply don't have a category for this type of stuff in our world, we don't know what to make of it," he says. "It is radically different in terms of provenance and product."

How is a hamburger made in a laboratory?

There are several steps and the procedure starts when muscle stem cells are taken from animals in a biopsy, says Mark Post, who is leading the project at Maastricht University.

Algae

Algae might be at the bottom of the food chain but it could provide a solution to some the world's most complex problems, including food shortages.

It can feed humans and animals and can be grown in the ocean, a big bonus with land and fresh water in increasingly short supply, say researchers. Many scientists also say the biofuel derived from algae could help reduce the need for fossil fuels.

Some in the sustainable food industry predict algae farming could become the world's biggest cropping industry. It has long been a staple in Asia and countries including Japan have huge farms. Currently there is no large-scale, commercial farm in the UK, says Dr Craig Rose, executive director of the Seaweed Health Foundation.

"Such farms could easily work in the UK and be very successful. The great thing about seaweed is it grows at a phenomenal rate, it's the fastest growing plant on earth. Its use in the UK is going to rise dramatically."

Like insects, it could be worked into our diet without us really knowing. Scientists at Sheffield Hallam University used seaweed granules to replace salt in bread and processed foods. The granules provide a strong flavour but were low in salt, which is blamed for high blood pressure, strokes and early deaths. They believe the granules could be used to replace salt in supermarket ready meals, sausages and even cheese.

"It's multi-functional," says Gaye. "And many of its properties are only just being explored. It such a big resource that we really haven't tapped into yet."

With 10,000 types of seaweed in the world, including 630 in the UK alone, the taste of each can vary a lot, says Rose.


Magnetic Field, Mantle Convection and Tectonics





Something startling here. It appears that the whole crust shifted thirty degrees around 120,000,000 years ago. Thus my conjecture regarding the Pleistocene Nonconformity does have a real precedent in time in space. The shift was also the correct thirty degrees as was the one that occurred 13,000 years ago.

Since I have been arguing for the recent shift been deliberate, I knew that there had to be a precedent to work from in order to attempt such a stunt. I presumed that it had been closer in time but this is much better. It clearly asks the right questions and suggests that it can be done again. We will be reaching those same conclusions over the next few years.

I have also proposed in this blog a plausible alternative explanation for crustal magnetism that conforms nicely to the available evidence. The explanation presented here flies in the face of all the evidence and is mostly hand waving comparable to theories of land bridges from sixty years ago.

Magnetic field, mantle convection and tectonics

by Staff Writers

Munich, Germany (SPX) Aug 02, 2012



It is known that the Earth's magnetic field is produced by convection currents of an electrically conducting iron-nickel alloying the liquid core, about 3,000 kilometers below the earth's surface. The geomagnetic field is highly variable, there are changes in Earth's magnetic field on a multitude of spatial and temporal scales.



On a time scale of tens to hundreds of millions of years, the geomagnetic field may be influenced by currents in the mantle. The frequent polarity reversals of Earth's magneticfield can also be connected with processes in the mantle.

These are the research results presented by a group of geoscientists in the new advance edition of "Nature Geoscience" on Sunday, July 29th. The results show how the rapid processes in the outer core, which flows at rates of up to about one millimeter per second, are coupled with the processes in the mantle, which occur more in the velocity range of centimeters per year.

The international group of scientists led by A. Biggin of the University of Liverpool included members of the GFZ German Research Centre for Geosciences, the IPGP Paris, the universities of Oslo and Utrecht, and other partners.

It is known that the Earth's magnetic field is produced by convection currents of an electrically conducting iron-nickel alloy in the liquid core, about 3,000 kilometers below the earth's surface. The geomagnetic field is highly variable, there are changes in Earth's magnetic field on a multitude of spatial and temporal scales.[i really do not think that this is known. What it is is a somewhat convincing explanation not subject to experimental confirmation. Calling it a liquid core does not make it so - arclein]

Above the liquid outer core is the mantle, the rock in which behaves plastically deformable due to the intense heat and high pressure. At the boundary between Earth's core and mantle at 2900 km depth there is an intense heat exchange, which is on the one hand directed from the Earth's core into the mantle.

On the other hand, processes within Earth's mantle in turn also affect the heat flow. The interesting question is how the much slower flow in the solid mantle influences the heat flow and its spatial distribution at the core-mantle boundary, and how this will affect the Earth's magnetic field which is produced due to the much faster currents in the Earth's core.


Key variable heat transfer

"The key variable is the heat flow. A cooler mantle accelerates the flow of heat from the hot core of the Earth, and in this way alters the also heat-driven convection in the Earth's core", said Bernhard Steinberger of the GFZ German Research Centre for Geosciences.


"Ocean floor sinking into the mantle due to tectonic processes can lead to cooling in the mantle. They cause at these sites an increased heat flow into the cooler parts, namely until they have been heated to the ambient temperature." That might take several hundred million years, however.

Conversely, the hot core of the Earth leads to the ascent of heated rocks in form of large bubbles, so-called mantle plumes that separate from the core-mantle boundary and make their way up to the surface of the earth. This is how Hawaii came into existence. This increases the local heat flux out of the earth's core and in turn modifies the generator of the geomagnetic field.

Reversals of the magnetic field

In the Earth's history, polarity reversals of the geomagnetic field are nothing extraordinary. The most recent took place only 780 000 years ago, geologically speaking a very short period of time.

The research team was able to determine that in the period of 200 to 80 million years before present, reversals initially happened more often, namely up to ten times in hundred million years. "Surprisingly, these reversals stopped about 120 million years ago and were absent for nearly 40 million years," explains GFZ scientist Sachs.

Scientists presume that the reason for this is a concurrent reorientation of the whole mantle and crust with a shift in the geographic and magnetic poles of about 30 degrees.

Known as "true polar wander", this process is caused by a change in density distribution in the mantle. If it increases the heat flux in equatorial regions, it would presumably lead to more frequent field reversals, if it decreases it, the field reversal might not occur.

White - Brown Fat Conversion Understood




Still early days and a long way from a safe drug protocol, however we are learning how to convert white fat cells into brown fat cells. This is good news that should allow superior fat loss protocols that work safely to limit accumulation through exercise. It has been far too easy for the body to retain fat while also improving in fitness.

At least we understand that conversion is possible and even inducible.

In the meantime, we get to wait.

Study Finds Mechanism That Turns White Fat Into Energy-Burning Brown Fat Raises Hopes for New Obesity and Diabetes Treatments

Released: 7/30/2012 4:50 PM EDT
Source: Columbia University Medical Center
Raises hopes for new obesity and diabetes treatments


Newswise — New York, NY (August 2, 2012) — Columbia University Medical Center (CUMC) researchers have identified a mechanism that can give energy-storing white fat some of the beneficial characteristics of energy-burning brown fat. The findings, based on studies of mice and of human fat tissue, could lead to new strategies for treating obesity and type 2 diabetes. The study was published today in the online edition of the journal Cell.

Humans have two types of fat tissue: white fat, which stores excess energy in the form of triglycerides, and brown fat, which is highly efficient at dissipating stored energy as heat. Newborns have a relative abundance of brown fat, as protection against exposure to cold temperatures.In adults, however, almost all excess energy is stored as white fat.

“Turning white fat into brown fat is an appealing therapeutic approach to staunching the obesity epidemic, but it has been difficult to do so in a safe and effective way,” said study leader Domenico Accili, MD, professor of Medicine and the Russell Berrie Foundation Professor at CUMC.

White fat can be “browned” with a class of drugs called thiazolidazines (TZDs), which increase the body’s sensitivity to insulin. However, TZDs have many adverse effects — including liver toxicity, bone loss, and, ironically, weight gain — which have limited the use of these drugs.

The current study was undertaken to learn more about the function of TZDs, with the ultimate goal of developing better ways to promote the browning of white fat.

Scientists have known that TZDs promote the browning of white fat by activating a cell receptor called peroxisome proliferator-activated receptor–gamma (ppar-gamma), but the exact mechanism was not clear. To learn more, Dr. Accili and his colleagues studied a group of enzymes called sirtuins, which are thought to affect various biological processes, including metabolism.

The researchers had previously shown in mice that when sirtuin activity increases, so does metabolic activity. In the present study, they found that sirtuins boost metabolism by promoting the browning of white fat. “When we sought to identify how sirtuins promote browning, we observed many similarities between the effect of sirtuins and that of TZDs,” said lead author Li Qiang, PhD, associate research scientist in Medicine at CUMC.

Sirtuins work by severing the chemical bonds between acetyl groups and proteins, a process known as deacetylation. “So the next question was whether sirtuins remove acetyl groups from ppar-gamma and, indeed, that was what we found,” said Dr. Qiang.

To confirm that the deacetylation of ppar-gamma is crucial to the browning of fat, the researchers created a mutant version of ppar-gamma, in effect mimicking the actions of sirtuins. The mutation promoted the development of brown fat–like qualities in white fat.

“Our findings have two important implications,” said Dr. Accili. “First, they suggest that TZDs may not be so bad — if you can find a way to tweak their activity. Second, one way to tweak their activity is by using sirtuin agonists — that is, drugs that promote sirtuin activity.”

“The truth is, making sirtuin agonists has proved to be a real bear — more promise than fact,” he continued. “But now, for the first time, we have a biomarker for good sirtuin activity: the deacetylation of ppar-gamma. In other words, any substance that deacetylates ppar-gamma should in turn promote the browning of white fat and have a beneficial metabolic effect.”

Dr. Accili’s paper is titled, “Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Ppar-gamma.” The other contributors are Ning Kon (CUMC), Wenhui Zhao (CUMC), Sangkyu Lee (University of Chicago, Chicago, Illinois), Yiying Zhang (CUMC), Michael Rosenbaum (CUMC), Yingming Zhao (University of Chicago), Wei Gu (CUMC), and Stephen R. Farmer (Boston University School of Medicine, Boston, Mass.)

This research was supported by grants from the National Institutes of Health (HL087123, DK58282, DK64773, DK063608, and RR024156).

The authors declare no financial or other conflicts of interest.

Columbia University Medical Center provides international leadership in basic, pre-clinical and clinical research, in medical and health sciences education, and in patient care. The medical center trains future leaders and includes the dedicated work of many physicians, scientists, public health professionals, dentists, and nurses at the College of Physicians and Surgeons, the Mailman School of Public Health, the College of Dental Medicine, the School of Nursing, the biomedical departments of the Graduate School of Arts and Sciences, and allied research centers and institutions. Established in 1767, Columbia's College of Physicians and Surgeons was the first institution in the country to grant the M.D. degree and is among the most selective medical schools in the country. Columbia University Medical Center is home to the largest medical research enterprise in New York City and State and one of the largest in the United States.

Upon its official opening in October 1998, the Naomi Berrie Diabetes Center at Columbia University Medical Center established a new standard of care for the 1.6 million people with diabetes in the New York area—combining world-class diabetes research and education programs with unprecedented family-oriented patient care. Named for the mother of the late Russell Berrie, founder of RUSS™ Toys, the center is today recognized as the most comprehensive diabetes research and treatment center in the tri-state region and has been designated a national “Diabetes Center of Excellence” – one of only three in the state of New York. Approximately one hundred faculty and students, affiliated with the Center, conduct basic and clinical research related to the pathogenesis and treatment of all forms of diabetes and its complications. For more information, visit www.nbdiabetes.org.



Pterosaur Sighting in Georgia




Another recent pterosaur sighting in the Eastern USA a few days back is reported. As mentioned, what is happening, is that witnesses are now locating internet sites able to report what they saw and in the process we are beginning to build a body of work. It will take some time but sooner or later this will become as well organized as the BFRO were the witnesses are reinterviewed and in the process have their credibility established.

This witness has not been questioned yet as to apparent size, nor has the son.

What is slowly emerging is basic confirmation that these creatures do exist. There is even a photo out there in which a group of hunters are showing of a trophy and it comes from long before it could be photo shopped. So we are going from one report that could be dismissed plausibly to were several reports are now extant and plausibly a mass of reports are out there just waiting for publicity to draw them in.

As posted in the past, the key to all this is to understand that all such creatures are nocturnal feeders and are normally very shy of humanity, although that may be now changing since we no longer have millions of teenage boys out there with a hunting rifle as we did up to the 1950's.



Pterosaur Sightings in Georgia

http://naturalplane.blogspot.ca/2012/07/pterosaur-sightings-in-georgia-on.html

On Wednesday, July 18, 2012, a lady was driving with her two sons on Highway 27, in Franklin, Georgia, around 8:15 a.m., when they saw what she called a “flying dinosaur.” In her email to me, she said, “I was so shocked at what I was seeing I started yelling to my sons to look up look up. I ask my oldest ‘do you see what I’m seeing?’ and he goes ‘Wow!’”

The lady’s son told his mother that it looked like a “pterodactyl.”

I asked the lady some questions:

Q: Did it have a tail?

A: Yes it it had a tail, a long one.

Q: Was the creature flapping its wings or just gliding?

A: It was just gliding across [the] road . . .

Q: About how high off the ground was the creature?

A: I can’t really say how high but low enough that I knew it wasn’t a big bird.

More Sightings Near Winder, Georgia (recent post)

. . . about a year and a half ago, maybe a little more, I saw what I believe to be the same animal from directly below, traveling fast . . . The tail is what riveted me, you could see the shape on the end . . . it stuck straight out.

A Modern Pterosaur in Georgia (older post)

Those two flying creatures might be of a rare species, normally nocturnal but temporarily displaced by a storm, perhaps a pair flying in daylight out of necessity. If they are nocturnal, Georgia certainly has many places for creatures to hide while sleeping in daylight.

Thanks to Jonathan Whitcomb - Live Pterosaur

Live Pterosaurs in America: Not extinct, flying creatures of cryptozoology that some call pterodactyls or flying dinosaurs or prehistoric birds

Friday, August 10, 2012

Giant Carbon Capturing Funnels in Southern Ocean





If you happen to be skeptical of climate modeling, this makes it a rout. A powerful nonlinear effect is dynamically responsible for injecting 40 % of the oceanic CO2 into the deep. Ignoring this is akin to ignoring tornadoes and we have just discovered it. The real problem is that we need a really good three dimensional dynamic model of the Ocean. From that it becomes plausible to model the overlying atmosphere. Perhaps one day we will be able to track and follow the heat.

Otherwise we naturally fall into the error of assuming the atmosphere is the dominant driver. A little like describing cooking and forgetting the role of the heat source. On Earth we have two heat sources. One is the sun and the other is the Ocean and to a far lesser degree the land surface.

That is the principle reason that I suspect that the key driver for the abrupt appearance of a little ice age happens to be an oceanic current flow transition of some sort. It would only need an inversion of cold water over the Gulf Stream for even a few years to wreak Europe and drop the average temperature by a couple of degrees. I can imagine it and we do not know if it is possible. More likely the real scenario will be a complete surprise.

Giant carbon-capturing funnels discovered in Southern Ocean

Aug 1, 2012



A team of scientists from the UK and Australia has shed new light on the mysterious mechanism by which the Southern Ocean sequesters carbon from the atmosphere. Winds, vast whirlpools and ocean currents interact to produce localized funnels up to 1000 km across, which plunge dissolved carbon into the deep ocean and lock it away for centuries. Critically, these processes themselves – and the Southern Ocean's ability to affect global warming caused by human activities – could be sensitive to climate variability in as-yet-unknown ways.

Oceans represent an important global carbon sink, absorbing 25% of annual man-made CO2 emissions and helping to slow the rate of climate change. The Southern Ocean in particular is known to be a significant oceanic sink, and accounts for 40% of all carbon entering the deep oceans. And yet, until now, no-one could quite work out how the carbon gets there from the surface waters.

"We thought wind was the major player," says lead author of the new study, Jean-Baptiste Sallée of the British Antarctic Survey. "The ocean is like an onion – in layers – and there is very little connection between the surface and deep layers," he explains. When strong winds displace a large slab of surface water and cause it to accumulate in a specific region, the localized bloat in the surface layer gets injected downwards into the ocean's interior. But this kind of wind action alone should have a fairly uniform effect over vast swathes of ocean – which is not what the scientists measured.

Subduction hotspots

Scrutinizing 10 years of temperature, salinity and pressure data from a fleet of 80 small robotic probes dotted around the remote Southern Ocean, the researchers discovered that surface waters are drawn down – or subducted – at a number of specific locations. This occurs due to the interplay between winds, dominant currents and circular currents known as "eddies". "You end up with a very particular regional structure for the injection of carbon," says Sallée, describing 1000 km-wide funnels that export carbon to the depths.

The team pinpointed five such zones in the Southern Ocean, including one off the southern tip of Chile and another to the south-west of New Zealand.Elsewhere, currents return carbon to the surface in a process known as "reventilation", but overall, the Southern Ocean is a net carbon sink.

Carbon bottleneck

The mechanisms governing atmosphere-to-ocean carbon transfer – the mechanical mixing action of wind and waves, and biological uptake by micro-organisms in the sunlit top layer of water – are already well understood. The step that determines the rate of the oceanic uptake of carbon, according to co-author of the study, Richard Matear of Australia's Commonwealth Scientific and Industrial Research Organization, is the physical transport of this dissolved carbon from the surface waters into the ocean interior. "Our study identifies these pathways for the first time," he says.

Understanding these subduction pathways fully is key to predicting how climate change might alter the Southern Ocean's carbon sequestering capabilities. Both global warming and the Antarctic ozone hole increase the temperature gradient between the equator and the pole, which intensifies the southern hemisphere winds. Climate models predict that stronger winds could stir up deep waters, especially in violent seas such as the Southern Ocean, and result in a net release of carbon back into the atmosphere.

"What we don't know yet is the impact of climate change on eddy formation," says Sallée. Eddies arise from oceanic instabilities caused by extreme gusts of wind, intense surface heating or cooling, or strong currents meeting uneven bottom topography, but tend to escape the granularity of even the most detailed climate models. "We can speculate that if wind increases, there will also be more eddies to counterbalance its effects," considers Sallée. "But it's a question we don't know how to answer yet. And it's a big incentive for climate models to refine their grid."

Improving climate models

Ocean-carbon-cycle expert Corinne Le Quéré, director of the Tyndall Centre for Climate Change Research, UK, who was not involved in the study, echoes Sallée's call for improved understanding of wind-eddy interplay. "Southern Ocean winds have increased in the past 15 years in response to the depletion of stratospheric ozone," she explains, adding "There's a lot of discussion right now about how [wind-induced changes] are then counterbalanced by changes in eddies."

Because of this, today's climate models diverge when it comes to predicting the future carbon sequestration response of the Southern Ocean. "I think this [paper] is really the first time that we have such small-scale resolution in the exchange of carbon in the ocean from observation directly," says Le Quéré. "The natural next step will be to take climate models and see how well they're performing spatially and [temporally]...this study can really help constrain which are the good models."

Malaria Breakthrough





This is great news because it suggests that a vaccine can be manufactured that through multiple applications will confer real immunity.  There are presently convincing strategies out there able to slash populations of the mosquito but there will always remain reservoirs of infection waiting to bite.  Thus those who must accept exposure do need a true immunization protocol.

Otherwise I am growing optimistic that the various strategies presently been implemented particularly including simple nets will succeed in driving this scourge out of humanities life way.

We have continued to note continued and expanding progress over the past five years of this blog.

Malaria breakthrough by Australian researchers


Scientists in Australiasay they’ve made a breakthrough in the fight against malaria by uncovering a key protein in people who have developed an immunity to the disease.

Researchers at Melbourne’s Burnet Institute analyzed the antibodies of adults and children in Kenyawho had become immune over time to the parasite, carried by mosquitoes.

James Beeson, head of the institute’s Centre for Immunology and senior author of the study, said his team examined a key malaria protein called PfEMP1.

“The puzzle has been, what is the key point of attack of the immune system against malaria? We’ve established that one particular protein of malaria is the key point of attack of the immune system,” said Beeson.

Scientists discovered certain Kenyans had developed an immunity to that protein, which means the protein could be a target for a future vaccine.

Specifically, the team studied children between ages of one and 10, as well as adults, and the number of times they had gotten malaria. The more times they had suffered the disease, which causes up to a million deaths year, the more antibodies they had.

According to the study, “repeated infections over time are required to generate antibody responses toward [the protein].”

Beeson said new research will focus on developing a vaccine to induce that immune response to the protein.

Malaria is caused by a parasite called plasmodium, which is transmitted through the bites of infected mosquitoes. Symptoms of malaria include fever, headache and vomiting, and usually appear between 10 and 15 days after the bite.

When untreated, malaria can quickly become life-threatening by disrupting the blood supply to vital organs.

The study, published in the Journal of Clinical Investigation, also involved research by University of Melbourne and the Kenya Medical Research Institute.

Signs of a Romney Victory




This is not ever going to come from the media that willy-nilly propelled Mr Obama into the White house as the most unexamined candidate in history. It finally turned out that he was a classic Marxist liberal arts professor who followed that dream deep into his career and was molded accordingly. Most likely his wife balanced his check book.

Now he must run on his record and that record begins and ends with one salient reality. He ignored the housing crisis in every way shape and form. Even Hoover did not ignore the depression ill advised as his prescriptions were. Today we do know better and a lot could have been done as I spelled out myself four years ago. Today, that market only now is seeing its first signs of life.

In the meantime, this election is Mr Romney's to lose and I can not imagine quite how this could be accomplished. The analysis below truly shows just how daunting Obama's task has become. Usually elections are won or lost between two well matched candidates within one percentage point. Right now I suspect that the real spread out there exceeds five percent which can still be cloudy in the poling.

We are looking at a Reaganesque landslide in the making even if Obama is able to hang on to his core. The American people know who Mr Obama is today and they will simply not want another four years of his performance. Recall they are all getting the bill for Obama-care. Is anyone paying less?


The Signs of a Romney Victory

Posted by Evan Sayet on Jul 30th, 2012



As I study the news looking for clues as to who is going to win the White House in November, I am struck by how, no matter where I look – from the most obvious to the things only a political junkie finds under a rock or in some tea leaves, etc. – every single indicator (big and small) points to a Romney victory and, in fact, something awfully close to an electoral college landslide.  While I will, of course, discuss the polls, the vast majority of my analysis comes from observation and common sense.

Let’s first establish a baseline.  Mark Levin asked a room full of folks at the Ronald Reagan library recently, “Do any of you know a single person – even one – who didn’t vote for Obama in 2008 who plans to vote for him in 2012?”  The answer, of course, was “no.”  Not a single person in the room knew a single person who Obama had, in the course of his presidency, convinced that he was better than they’d expected him to be.  Conversely, we all know at least one person – and I personally know more than a dozen (because I ask) – who voted for Obama in 2008 who nothing less than rues the day.

Given that Obama’s 2008 victory was, while large in size, in no way numerically historic, and that he had all sorts of advantages (being a blank slate, following eight years of war after 9-11, etc.) that he won’t have this time, Obama’s chances for a second term are significantly lower based on just Levin’s observation alone.  But, for Obama, it gets worse.

Not only is the pool of potential Obama supporters way down from 2008, so too is the enthusiasm amongst those who still, to one degree or another, prefer Obama over the alternative.  Whereas, not all that long ago, Obama could pack football stadiums and basketball arenas with ease, not even the lure of attending the big campaign kick-off event was enough for Obama supporters to come, leaving the venue half-empty.  If you can’t get your supporters to an historic rally in the spring, there’s little chance they’re going to drive to the polls in the dead of winter.

Worse still for the President is that, in order for him to have pulled off his original victory, he needed unprecedented enthusiasm (manpower, money, votes and more) from a handful of the Democrat Party’s traditional constituencies such as blacks, Jews and those under twenty-five.  If these numbers were to simply return to normal, then Obama’s chances of a second term are only further diminished.  But logic and evidence suggests Obama’s support from these groups will be less – in some cases far less – than what any and all Democratic nominees can count on.  This is because, thanks to his policies, each of these constituencies has a specific and rightful grievance against this president.  These grievances not only dampen their enthusiasm for Obama but, in many cases, turn them against him.

Blacks, for example, particularly hard hit by the liberals’ fifty-year war against the traditional family, have taken singular exception to Obama’s clearly politically motivated endorsement of homosexual marriage; Jews are rightly concerned about the most virulently anti-Israel President since the Jew-hating Jimmy Carter, while the young who have (attempted) to enter the workforce are suffering the realities of looking for a job in an Obama economy and can’t be wholly unaware that each dollar of new deficit Obama racks up will be expected to be paid for by them.  Will Obama still take a majority – even a large majority – of votes from these constituencies?  Of course.  But in every way – manpower, financial contributions and votes – not only will Obama fail to receive record support as he did in 2008, or even the usual support a Democrat needs, he will fall short and even see some of that support drift to Romney.

There is one more constituency that Obama had to win – and win big – in order to win the White House in 2008 that is now not only less supportive but greatly disgruntled.

They are the independents (and even some right-of-center Republicans) who might well have disagreed with many of Obama’s policies and prescriptions but who were willing to accept four or eight years of an Obama presidency in exchange for the promise his rhetoric offered of a more civil America.  Higher taxes, more wasteful spending, they believed, were an acceptable price to pay for a “post-partisan” America and maybe even a “post-racial” United States.

After four years of the most viciously partisan presidency in anyone’s living memory and the most race-charged administration most of us can ever recall (not to mention the vile tactics so closely associated with Obama and his administration, which are named after his hometown, “The Chicago Way”), those who voted against their policy preferences to elect the guy with “hope” and “change” are and can be nothing less than disgusted with him.

The category pollsters use to measure this sentiment is called “likeability” (or “personal favorability”) and Obama’s rating in this category is plummeting. The only way that a failed president can win a second term is if the people like and trust him. According to the latest New York Times poll, Obama’s tactics have left him “favorable” to only about one out of every three voters (36 percent).

Other recently released data suggest that Obama is in big trouble as well.  Not the least of them is the Obama camp’s inability to get people to donate to their campaign.  Not all that long ago, a confident (arrogant?) Obama team was predicting so much support that they’d bring in more money than any other campaign in human history – over one billion dollars.  So far, not only has Obama not come close to being the greatest fundraiser in all of human history, he’s not even the top fundraiser in his two-man contest for the presidency.  In fact, he trails Romney’s financial support by a wide margin.

This is important not just because money is a plus in any campaign (though not nearly the plus that many make it out to be) but because it is a tangible action.  Answering the telephone and saying “yes” or “no” ten times to some stranger from a polling company doesn’t require much of a commitment.  People who donate to a campaign are likely to do even more for that campaign and they are almost guaranteed to do the one thing that matters most: vote.

And there is more evidence of an impending Romney victory to be found in how each camp is conducting its campaigns.  The strategies employed, the rhetoric chosen, all of these things reflect the campaign’s belief about where they stand at any given moment in the contest.

For example, it is simply a truism in politics that a candidate who believes he’s winning stays on the message that put him in the lead.  Those who believe they’re losing change their message until they find one they believe is a winner.  Romney has run almost the entire time on a single, compelling and positive message.  At its heart it’s something like “America is in economic dire straits.  I’ve made my fortune and my reputation saving big and complex things (the Olympics, major industries, etc.) from economic dire straits.  Vote for me and I’ll save America.”  Romney’s staying on that message makes clear that, at the very least, his own internal polling and other evidence has convinced his campaign that he’s winning.

Obama, on the other hand, seems to be premiering a new message just about every week or two. It’s a practice of the desperate not so delicately known as “Throwing sh-t against the wall hoping something sticks.” Clearly, then, the Obama camp’s inside information is telling them the same thing my analysis and Romney’s intelligence is telling us: their messages aren’t working and that they trailing in the election.

Making matters worse for the president is that, while Romney’s message is positive and promising, the tenor of Obama’s ever-changing messages has been singularly negative.  As a failed president, since he can’t run on his record, the only option available to him is to try and render the alternative so far beyond the pale that, no matter how bad Obama is, the alternative is just unacceptable.  In other words, the entirety of Obama’s message (whatever it is at the moment) is comprised not of words like “Vote for me because” but only “Vote against him because…”  Such an unrelenting campaign of negativity – the only option for Obama – only serves to further undermine the only thing that could possibly help him win: his “likeability.”  It’s a catch-22 from which Obama is unlikely to be able to escape.

Making matters worse still for the current president is that, in these ever-changing messages, Obama’s case against Romney has ranged from beneath the dignity of a president of the United States to beneath contempt to beneath sanity.

In a short time, then, the Obama team’s message went from “Vote against Romney because he once had a dog carrier built that attaches to the roof of his family car,” to “Vote against Romney because fifty years ago he engaged in a high school prank” to “Vote against Romney because he’s a successful businessman (and therefore probably a felon)” and so on.  If this is all he’s got – and apparently it’s all he’s got – start making plans to attend Romney’s inaugural.

But it’s even worse for Mr. Obama because, not only did these ludicrous attacks utterly fail to move the needle even the slightest in his direction, each and every one of them totally backfired.  Some, disastrously so.

For example, while no one cared about Romney putting his dog in a carrier on the roof of his car, it allowed Obama to become a laughing stock for happily admitting that he had, at least once, put a dog on the roof of his mouth.  And, while no one cared about a childhood prank Romney helped pull off a half-century ago, it did lead to questions about Obama’s admission inDreams From My Father that, at about that same age, he had shoved a young woman.  And while no one was up in arms about the fact that a wealthy man had investments in countries outside of America, it not only exposed the hypocrisy of the accusers when it turned out that virtually every Democratic senator and congressman had similar investments, but it raised questions about how so many supposed “public servants” had amassed the kind of money usually associated with titans of industry.

These failures all paled in comparison, however, to the utter fiasco that was Obama’s attempt to sell the message: “Vote against Romney because Republicans hate women.”  Given how audacious a statement this is — how horrible it would be if it were true and how despicable the accusation if it wasn’t — the people waited for the President of the United States to produce some evidence to support his claim.  When all Obama could produce was a woman named Sandra Fluke whose “proof” consisted of opposition to tax-payers picking up the tab for her condom use, the President’s credibility took a massive hit…and Fluke was soon jettisoned (anyone hear anything from or about her since?)

While the Obama camp quickly threw Ms. Fluke under the bus, they weren’t quite prepared to give up their effort to discredit Romney and all Republicans as “women haters.”  Soon – with great fanfare and (media-generated) publicity – they unveiled their masterpiece: an animated “everywoman” they named “Julia.”  The campaign soon became the stuff of pure mockery, doing nothing to help Obama’s chances in November.  In fact, while it did nothing to advance the phony narrative of Republicans as being “at war” against women, what it did was to expose the very real misogyny of the liberal movement.  While the storyline followed the feminist meme, “A woman needs a man like a fish needs a bicycle,” it also made clear that these liberals believe a woman desperately needs a nanny (state) to accomplish even the simplest of things in her life.

But even more telling about the state of the race than the ever-changing slanders that serve as Obama’s campaign themes, is who the messages are targeting.  The fact that, three-and-a-half years into his presidency, a Democrat is still desperately trying to scare single women into voting for him means that Obama’s internal polling must be telling him that he’d better take desperate measures just to shore up a constituency that should have been his from day one.

Similarly, this is the only possible explanation for Obama’s desperate ploy to suddenly end his “evolving” and embrace homosexual marriage.  It is hard to believe that after more than fifty years of life, twenty-five years in academia or as a professional speechifier and three-and-a-half years as president, he’d suddenly had an epiphany that couldn’t wait just a couple more weeks until after what some believe will be a very close election.  The only possible explanation for the timing of Obama’s announcement was that he needed to placate the LBGT community, and the only reason he’d need to placate them is because his polling showed he hadn’t even shored up their vote this late in the game.  If a liberal Democrat isn’t even sure of the support from the LGBT movement a few weeks before Election Day, chances are good he’ll be packing his bags come January.

Finally, more information can be gleaned from the choices the two camps are making in how they conduct their campaigns. While some aren’t thrilled with what they perceive to be Romney’s “play it safe” style, it does indicate that his internal information is telling him that he has a sizeable lead. Whether this “four-corner” approach is wise or not, time will tell.  Nonetheless, it does seem to be borne of the old adage, “Never kill a man who’s already committing suicide.”

Another indicator along those same lines is that, while Obama is spending every penny he takes in and then a full twenty percent more (in debt), Romney’s “burn rate” is about eighty percent, saving twenty cents of every dollar the way prudent people save for the possibility of a rainy day.  Obama’s spending every penny he can get his hands on as fast as he can get his hands on it seems to indicate his understanding that he needs to just survive July at any and all costs and deal with the future if he makes it.

And it’s not just Obama’s desperate attempts to buy his way back into contention that is telling, so too is just what his campaign is spending that money on.  Spending this much money on television ads in July shows a degree of desperation.  Spending this much money on paid staff seems to be an indication Obama is lacking for the support of volunteers and so on.

Finally, the most telling of all is how much Obama is spending on polling.  Polling to judge the state of the race in July is not much of an imperative, especially when there are so many free sources for this information (Rasmussen, Gallup, etc.)  Typically such polling is conducted at this time to test various campaign themes and messages.  Obama’s frantic spending on focus groups and other such polling indicates that he is desperately searching for a message that will work and that he hasn’t yet found one.

Believe it or not, there are many more clues pointing towards a Romney romp that I haven’t yet touched upon (the bounce he’ll receive from announcing his running mate, the fact that Obama won’t have his teleprompter if/when they debate, etc.)

But I’m already on page five and, well, no matter where I look, all I see is a Romney victory in November.  In fact, it looks like it might even be a romp.